If I reboot the server it is fine, but after a few minutes the RAM just goes, and this is only with one agent logged in and no one else doing any work in the system at all. Our database size is about 2.5GB and we have about 65,000 tickets.
I have some screenshots showing what we see:



The most common processes we see in this one above are the PostMasterMailbox.pl, GenericAgent.pl and PendingJobs.pl. It is never the same process taking the RAM.
Any ideas?