So my very small otrs deployment has 2 queues. One for every product line. These products are very different so bare with me

All productlines have their own support email address.
I have different signaturess for an agent depending on the queue. So far, so good.
But can I also have the email address of my agent (when I reply to a ticket to an external user) switch with every queue?
Looking forward to any and all hints, tips, trics, etc.
Warm regards,
Jeroen Baten